Familial Mediterranean Fever Symptoms
Familial Mediterranean fever is an inflammatory disorder that causes recurrent fever and inflammation that causes pain in the abdomen, lungs, and joints. Therefore, you need to know about Familial Mediterranean Fever Symptoms in the following article.
Family-related Mediterranean illness is an inheritable disease that typically affects those who are of Mediterranean origin – which includes Sephardic Jews, Arabs, Italians, Armenians, and Turks. But the disease can spread to any ethnicity.
Familial Mediterranean fever is usually diagnosed during childhood. While there is no cure for this disorder, you may be able to relieve the signs and symptoms of familial Mediterranean fever – or even prevent it altogether – by sticking to your treatment plan.
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So, let’s take a look at the full review of Familial Mediterranean Fever Symptoms below.
What is Familial Disease
What is Familial Disease. “Familial” disorders are the ones that seem to be caused by a genetic factor and affect more relatives than would be expected just by chance. But, a specific reason or cause for the genetic component is not yet known.
What is Familial Mediterranean Fever
Before knowing Familial Mediterranean Fever Symptoms, here is an explanation of ‘What is Familial Mediterranean Fever’. Family Mediterranean fever (FMF) is a disease caused by genetic changes (mutations) within the MEFV gene. Mutations within the MEFV gene can affect how a specific protein is known as Pyrin, plays a role in the control of inflammation in the body. Inflammation that is not controlled can cause frequent (recurrent) attacks (attacks) of symptoms of fever and pain in patients suffering from FMF.
The signs of an attack may include fever, headache, and discomfort, caused by inflammation of the tissues around the stomach (peritonitis) joints (synovitis), and the lung tissue (pleuritis) as well as other organs. There are also instances of people who suffer from red patches swelling, tender and tender the skin (Erysipelas-like the erythema).
Recurrent attacks typically last from one to three days and range in intensity. In between attacks, a sufferer usually feels normal and these periods of symptom-freeness could last for days, or even for years. Factors like hormonal cycles, infections, and stress could influence the frequency of these attacks. In the majority of cases, the first attack is experienced at or before 20 years of age. Children with FMF may have intermittent fever, which is the sole manifestation.
Certain people with FMF have a buildup of protein (amyloidosis) throughout different parts of the human body. including the kidney. If untreated it can result in the possibility of life-threatening kidney failure. Patients who do not suffer the typical symptoms of FMF are still susceptible to developing this kind of kidney damage.
Untreated FMF may also cause diminished fertility.
A few people with two mutations within the MEFV gene might not experience any symptoms or signs, and those who have only one mutation within the MEFV gene might be afflicted with symptoms. In there is no personal or family history of inflammatory disease, MEFV mutation status is not able to be used to estimate a person’s risk for developing symptoms.
Familial Mediterranean Fever Symptoms
Some of you may be wondering what are the Familial Mediterranean Fever Symptoms. Signs and symptoms of familial Mediterranean fever usually begin in childhood. Familial Mediterranean Fever Symptoms, occur with an attack of the disease called a disorder that lasts one to three days.
Familial Mediterranean Fever Symptoms. The symptoms and signs of family-based Mediterranean fever are:
- Stomach pain
- Chest pain
- Aches, swollen joints
- Constipation followed by diarrhea
- The legs are covered with a red rash particularly below the knees
- Muscle ache
- Swollen, tender scrotum
The symptoms mentioned above also include familial Mediterranean fever carrier symptoms. Between attacks, you will probably feel normal. The period between one symptom and another is only a few weeks or a month at most.
How common is Familial Mediterranean Fever
How common is Familial Mediterranean Fever. FMF is prevalent in ethnic groups within the Mediterranean region, with notable individuals who are of Armenian, Arab, Turkish, Iraqi Jewish, and North African Jewish ancestry, where the incidence is between 1 in 200 and 1 in 1000 individuals. In other populations, the incidence of FMF is less.