Acne is a skin disorder associated with excess oil production (sebum). Acne occurs when the hair follicles or place of hair grow are clogged with oil and dead skin cells. It causes inflammation as well as blockages in the pores of the skin. to overcome this, you need to know minocycline for acne has proven to be quite potent against acne.
This inflammation is characterized by the appearance of small lumps (which sometimes contain pus) over the skin. This skin disorder can occur in parts of the body with the most oil glands, namely on the face, neck, upper chest, and back.
Some common symptoms of acne include:
- Lumps are reddish or yellow (because they contain pus).
- Small lumps (papules) appear above the skin.
- The sensation of heat or burning due to the presence of inflammation.
- Itching of the lumps arises.
- If compounded by inflammation:
- Pustules, which are small lumps at the end of which there is pus.
- Papules, which are small lumps of redness accompanied by pain.
- Nodules, which are hard lumps that form below the surface of the skin and can be accompanied by pain.
- Cysts, which are large lumps that form below the surface of the skin that contains pus and is accompanied by pain.
Causes of Acne
Some of the conditions that cause acne, among others:
- Excessive production of sebum, a substance produced by oil glands to prevent dry skin.
- Blockage in hair follicles by a mixture of dead skin cells and sebum.
- Propionibacterium acnes-type bacteria develop, clog hair follicles, and cause inflammation.
- Genetic or hereditary factors, if one parent has acne problems,
- Clogged follicles can swell and form whiteheads or blackheads when exposed to the outside world. The condition should not be underestimated, because it can develop into pustules, papules, nodules, or even cysts if contaminated by skin bacteria.
- Hormones, namely during the activity of excess androgen hormones or when hormonal changes occur during menstruation.
- The use of cosmetics is not always tolerated by everyone’s skin.
- Stress can affect a person’s lifestyle, including in a diet that can trigger acne.
To minimize the occurrence of acne is important for you to know minocycline for acne is quite potent to treat acne.
What is minocycline?
Minocycline is one of the tetracycline antibiotics used to treat various types of bacterial infections, such as urinary tract infections, respiratory tract infections, severe acne, gonorrhea (gonorrhea), fever due to insect bites, and chlamydia;
Minocycline is known as the most active tetracycline antibiotic especially for staphylococcal bacteria that are resistant to certain antibiotics. Although it has a wide spectrum in eradicating bacteria including Niserria meningitidis, the drug is not recommended to be used as prophylaxis or prevention due to its side effects (vertigo and dizziness);
About the drug minocycline
Types of drugs: Tetracycline antibiotics
Categories: Prescription drugs
Uses: Treating bacterial infections
Consumers: Adults and children
Pregnancy: Category D
Preparations: Capsules, injection fluids
Brand: Ference, Nomika
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How does minocycline work?
Minocycline works by getting into bacterial cells through the lipid bilayer boundary or passively diffused through the bacterial porin channel.
The drug inhibits protein synthesis by binding to 30S ribosome subunits and–possibly also–subunit 50S. This condition will prevent the binding of tRNA to mRNA thus disrupting protein synthesis.
How to react to minocycline?
Consult your doctor before you take minocycline if you are taking nonprescription medications, herbal supplements, or vitamins. Because it can interfere with the way minocycline works.
Minocycline can also react by:
- Birth control pills
- Blood thinners
- Penicillin antibiotics
- antacids containing aluminum, magnesium, calcium, or iron
- acne medications containing isotretinoin
Minocycline can cause birth control pills to be less effective, so one should use alternative protection when taking the drug.
Research shows that antibiotics like minocycline work better when combined with other acne treatments than alone. A doctor may prescribe topical acne medications, such as retinoids or topical antibiotics, which a person uses on the skin at the same time.
Other topical options include benzoyl peroxide, which is available in recipes and formulas that are sold freely.
One should follow the doctor’s advice about minocycline dosages and any topical acne products.
Some types of drugs that can interact with minocycline are:
- Concurrent use of antacid drugs containing Al, Fe, Mg, Zn can decrease the absorption rate of these drugs;
- The drug can decrease the effectiveness of oral contraceptive drugs;
- Can interfere with the bactericidal effects of penicillin;
- Can enhance the anticoagulant effect of blood;
- Increases the risk of nephrotoxicity if used in conjunction with diuretic drugs;
- Increases ergotism when used in conjunction with ergot alkaloids;
- Potentially fatal if used in conjunction with methoxyflurane as it can cause renal toxicity.
Dosage and how to use minocycline
Minocycline is available in dosage form and dosage strength:
Injection fluid: 100 mg;
Capsules: 50 mg, 100 mg;
Topical/subcutaneous: 1 gr.
The best dosage is the one recommended by your doctor. Commonly used dosages are as follows:
Treatment of vulnerable bacterial infections
Adult dosage: initial, 200 mg followed by 100 mg once every 12 hours. Maximum 400 mg/day.
Children’s dosage: >8 years old, early 4 mg/kg, then 2 mg/kg once every 12 hours.
Treatment of Vulnerable Bacterial Infections
Adult dosage: 200 mg per day divided into several doses.
Mycobacterium marinum infection
Adult dosage: 100 mg, 12 hours once for 6-8 weeks.
Adults: 100 mg 2 times a day for 5 days, followed by the administration of rifampicin.
Adults: 50 mg twice a day or 100 mg once a day. If bb > 45 kg: 1 mg/kg once a day.
Adult: 200 mg at the beginning, then followed by 100 mg once every 12 hours for 10-15 days.
Adults: 100 mg once every 12 hours for at least 7 days.
Unless complications of gonorrhea
Adult: early 200 mg, followed by 100 mg once every 12 hours, at least for 4 days, cultural examination should be carried out within 2-3 days after completing the therapy process.
Adult dosage: In the form of a subgingival cartridge with a dose of 1 mg is administered to the periodontal sac of the tooth. Giving in this way should be done by skilled medical personnel.
Instructions for use minocycline
Use minocycline after or before meals and it is recommended to drink plenty of water;
Always follow the doctor’s advice or instructions for use listed on the packaging before starting to consume it;
Use between one dose and another dose at the same hour distance, for example, twice a day means per 12 hours, three times a day means per 8 hours. To make it easier, try to consume it at the same hour every day;
If there is a missed dose due to forgetting, it is recommended to take it immediately during the next dose is still long about 5 hours or more. It is not permissible to double the dose of minocycline on the next drinking schedule in exchange for a missed dose.
Some categories are prohibited from using minocycline
Minocycline is not safe for everyone.
The following people should not take minocycline:
- people with sensitivity or allergy to tetracycline antibiotics
- pregnant and lactating women
- children under 12 years of age
- the person who has liver or kidney problems
- those who use birth control pills
- People who are taking certain medications, such as blood thinners and other antibiotics
Use in pregnant and lactating women
According to the United States Food and Drug Administration (FDA), minocycline is in category D for pregnant women. That is, the use of this drug is proven to pose a risk to the human fetus.
However, the number of benefits obtained if used in pregnant women can be considered (for example if medication is necessary to cope with a life-threatening situation or serious illness where safer drugs are ineffective or cannot be administered). Therefore, the use of minocycline should only be when it is needed and its usefulness is better than the effects.
Minocycline should not be consumed by nursing mothers as it is known to be extractable into breast milk and can affect the teeth and bones of babies, especially if treatment is carried out over a long time during breastfeeding.
Keep out of reach of children.
Store the drug in a sealed container at room temperature, away from heat, humidity, and direct light. Keep it from freezing.
Do not store outdated drugs or drugs that are no longer needed.
Ask your health professional how you should dispose of medications you don’t use.
Many risk side effects of minocycline use are as follows:
- Bleeding on the gums, redness and swelling in the mouth (for topical remedies);
- Belching and rising stomach acid;
- Increases sensitivity to sunlight;
- Pain in the joints and muscles.
Effects of overdose
Excessive use exceeding the recommended dosage can cause an overdose effect characterized by severe symptoms of dizziness, nausea, and vomiting. If this happens, contact the nearest hospital immediately for medical attention.
Tips to take care of acne skin
- Keep your face clean by washing your skin twice a day and after sweating but don’t wash too much.
- Moisten the face
- Apply acne treatment all over the face, not only on acne areas.
- Pat the skin gently and avoid rubbing with a towel and washer to minimize irritation.
- Wash hair regularly to control the oil on the scalp and around the hairline.
- Research acne products that are sold freely
- Avoid thick makeup
- Choose the right hair product
- Don’t touch your face too often
- Protect the skin from the sun
- Nourish the skin with the right foods
- Exercise regularly
- Avoid stress